http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101799473-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec4bbc641bb5ec5e62f7e0cd7f389840
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-544
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789
filingDate 2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55c7ebc9e3ad3c0c7372f46bce542dd2
publicationDate 2014-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101799473-B
titleOfInvention SPA-antibody tripolymer, cell treating kit containing tripolymer, preparation method and application thereof
abstract The invention relates to an SPA-antibody tripolymer, a cell treating kit containing the tripolymer, a preparation method and application thereof. The tripolymer comprises an anti erythrocyte antibody, an SPA and an antibody of a certain anti leukocyte antigen or other antigens. The tripolymer is combined with an erythrocyte through the anti erythrocyte antibody per se, the other antibody is combined with a corresponding leukocyte antigen (or other antigens), and then leukocyte (other cells, factors) and the erythrocyte are deposited through an erythrocyte sedimentation process or other methods of density gradient centrifugation and the like, thereby achieving the purpose of eliminating ingredients of corresponding cells and the like, connecting the erythrocyte with a corresponding antigen by the SPA, and being used as a mean for detecting a certain antigen. The invention has convenience and simpleness, and can be directly used for clinically separating and extracting stem cells/progenitor cells; and the collected and extracted stem cells/progenitor cells have no external markers. Meanwhile, the kit based on the tripolymer can be industrially produced so as to realize the popularization of the separation and purification technology of hematopoietic stem cells.
priorityDate 2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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