| abstract |
The present invention relates to the RNA of compound, it comprises the RNA of at least one and one or more oligopeptides compounds, wherein said oligopeptides has the function of the peptide (CPP) of penetration cell, there is 8-15 amino acid whose length and there is key residues and be selected from Arg, Lys, the empirical formula (Arg) of His, Ornn 1 ; (; Lys)n m ; (His)n n ; (Orn)n o ; (Xaa)n x .The invention still further relates to the method for transfectional cell or organism, thus apply complex RNA of the present invention.In addition, there is disclosed herein the pharmaceutical composition and test kit that comprise complex RNA of the present invention, and complex RNA of the present invention be used for transfectional cell, tissue or organism and/or for regulate, preferably induce or strengthen immunoreactive purposes. |