Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab8272d8dee739b574c817ca9d0e13bb |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 |
filingDate |
2010-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fcee68a757dfed3042ecd0ba9067023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1226f1d1d5f47b837868bcb91e940709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c85e2eab28cbba126275e4cab4f1a9ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c70fa07118ec52e429270c24a8aed5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4be8b43bb2ffef46704f65b7738f291 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28451f4bcf3807c55d97a0cad19c23cb |
publicationDate |
2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101785779-B |
titleOfInvention |
Separation and preparation of isovaleryl-spiramycin II |
abstract |
The invention relates to the separation of antibiotic and the application of the antibiotic in resisting infectious diseases, in particular to an isovaleryl-spiramycin II single-component compound. A kelimycin sample is separated by HPLC (high performance liquid chromatography) after crude separation, high-efficiency purification and post-processing, so as to obtain the pure isovaleryl-spiramycin II compound. Biological experiment results show that the antibacterial activity of the isovaleryl-spiramycin II compound is better than that of kelimycin and is much better than that of a control group. The invention lays the foundation for developing the clinical and effective isovaleryl-spiramycin II single-component antibiotic. |
priorityDate |
2010-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |