http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101781350-B

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00
filingDate 2010-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_696c2d74472b27a0c1aaf746c41884fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54b57bac4dc591a67d08bc39da32f2c
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publicationDate 2013-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101781350-B
titleOfInvention Method for purifying ursodeoxycholic acid by mixed solvent
abstract The invention provides a method for purifying ursodeoxycholic acid by a mixed solvent, which comprises three steps of preparing the mixed solvent, washing a cholic acid mixture and drying to obtain the ursodeoxycholic acid. The method is characterized by using the mixed solvent prepared from 1-80 parts of small molecule alcohol and 99-20 parts of small molecule ester by weight. The mixed solvent can selectively dissolve impurities of chenodeoxycholic acid, and the like in the cholic acid mixture and reserve the ursodeoxycholic acid. The mixed solvent not only reserves strong dissolving capacity of alcohol on the chenodeoxycholic acid, but also reserves the characteristic of ester for selectively dissolving the chenodeoxycholic acid. Under the premise of the same production capacity, the method for purifying the ursodeoxycholic acid of the invention can obviously reduce the consumption of organic solvent, saves the energy consumption of solvent recovery, and is suitable for preparing high purity ursodeoxycholic acid.
priorityDate 2010-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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