http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101762574-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ede1de2d4dddfbd45a76468af8c43038 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 |
| filingDate | 2008-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8983616b99a622ed8facab39a346614 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_001324d867f2f27f13ee33ff7e02a988 |
| publicationDate | 2013-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101762574-B |
| titleOfInvention | Method for enhancing stability of nano gold and biological detection method adopting the same |
| abstract | The invention provides a method for enhancing the stability of nano gold and a biological detection method adopting the same. Mononucleotide dNMP can better stabilize the nano gold than single-stranded DNA with the same composition and the same base concentration. Various nucleases with matrix selectivity can digest nucleic acid to form the dNMP. The property of the dNMP, which enables the dNMP to better stabilize the nano gold, is integrated with specific enzyme reaction, and the change of the color of the nano gold can be used to simply and conveniently detect various analytes including enzyme and DNA. The method greatly broadens the range of detected substances biologically detected by the unmodified nano gold, and increases the sensitivity of detection. Taking DNA detection for an example, the mole ratio range of a detecting probe and a target is broadened by three orders of magnitude. The method can be applied to the detection of various types of substances including micromolecules and heavy metal ions. |
| priorityDate | 2008-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.