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filingDate 2008-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94894834de1bee76b40ae431b568fbc1
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publicationDate 2010-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101744784-A
titleOfInvention Double-layer slow-release tablet with puerarin derivatives and preparation method thereof
abstract The invention discloses a double-layer slow-release tablet containing puerarin derivatives, which comprises a slow-release layer and a quick-release layer. The double-layer slow-release tablet is characterized in that the slow-release layer mainly comprises a puerarin derivative, a slow-release material, a filling agent and an adhesive, and the quick-release layer mainly comprises a puerarin derivative, a disintegrating agent and a diluting agent, wherein the weight ratio of the content of the puerarin derivatives in the slow-release layer and the quick-release layer is 7:3-8:2, and the weight ratio of the slow-release layer to the quick-release layer is (1-1.3):1. The invention also provides a preparation method of the double-layer slow-release tablet containing the puerarin derivatives. The release of a quick-release part in the double-layer slow-release tablet with the puerarin derivatives can enable a medicine to reach the effective blood concentration more quickly, and a slow-release part is slowly released and exerts the function of maintaining the stable and uniform effective blood concentration. Therefore, the effects of reducing the administration frequency and enhancing the compliance of a patient are achieved.
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