http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101685084-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88f3c3bda27035bd46a738027afa44f4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2008-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13341973defc2d36bbd474757216a8cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_651e6ec04bbd33b1581f77cc962753ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e85be66be55bdfb28e6b7782c5df9e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a06ed14a6eae0ee3002f59bd5641b71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4050dabea788c4e53dcd6fa3766cee78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48df1d740f3da7d43e193c890d4b689d |
| publicationDate | 2013-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101685084-B |
| titleOfInvention | Method for detecting methylnaltrexone bromide and impurity thereof by chromatography |
| abstract | The invention provides a method for detecting the impurity and the content in methylnaltrexone bromide and the preparation thereof, belonging to analytical chemistry field. The detecting method uses chromatography and the nonpolar stationary phase, in a mobile phase system using buffer solution as a mobile phase A and using a mixed solvent of water and an organic solvent as a mobile phase B, the impurity and the content in methylnaltrexone bromide and the preparation thereof are detected by eluting and separating in gradient. The method can effectively separate the methylnaltrexone bromide from the known intermediate impurity and the unknown impurity, and can effectively detect the methylnaltrexone bromide. The method can also used for quality control of methylnaltrexone bromide and the intermediate thereof. The method of the invention has advantages of strong selectivity, high precision and easy operation. |
| priorityDate | 2008-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.