| abstract |
The invention provides antibody, comprise chimeric human antibodies, recombinant antibodies, synthetic antibody, and their nucleic acid of encoding, prepare and use the method for these immunoglobulin (Ig)s.The invention provides the embodiment of the polypeptide of restructuring and synthesis and the nucleic acid of these polypeptide and/or antibody.Present invention also offers the polypeptide comprising or be made up of joint owner framework region or " independent total framework (ICF) ", to encode their nucleic acid, and comprising library and the test kit of these ICF and/or antibody of the present invention, they are independent form and the form in combinatorial library and combination. |