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filingDate 2008-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0faae30d777547d5d1cbb698211ec188
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publicationDate 2010-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101675020-A
titleOfInvention Method for synthesizing optically active carbonyl compounds
abstract The present invention relates to a method for synthesizing optically active carbonyl compounds by the asymmetric hydrogenation of aplha, belta-unsaturated carbonyl compounds, in the presence of optically active transition metal catalysts which are soluble in the reaction mixture and which have at least one carbon monoxide ligand. For the synthesizing of the optically active catalyst which is to beused and which has at least one carbon monoxide ligand, a catalyst precursor is pretreated with a gas mixture containing carbon monoxide and hydrogen. Excess carbon monoxide is removed from the catalyst so obtained before the latter is used in the asymmetric hydrogenation, and the asymmetric hydrogenation is carried out in the presence of additional carbon monoxide supplied to the reaction mixture.
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