Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd708a84f841d099bd81f8e8d72a610a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4525 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-166 |
filingDate |
2007-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc830312e4a64191c82c81f88481af9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1403f4aa7b08cb14c76d88f059cc82b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c30bac0238a89ffb3f88d983fe6a5a7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_864714f0faa3a3370e1504a3319ff72d |
publicationDate |
2013-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101674820-B |
titleOfInvention |
Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy |
abstract |
Provided herein are methods for using at least one histone deacetylase inhibitor to decrease cellular DNA repair activity, methods for monitoring the decrease of cellular DNA repair activity using at least one biomarker, methods of treating cancer by using at least one histone deacetylase inhibitor to decrease cellular DNA repair activity in combination therapy, methods of combination therapy where at least one histone deacetylase inhibitor interferes with a DNA repairing mechanism involving RAD51, methods for predicting a induction time period between a first administration of at least one histone deacetylase inhibitor and a second administration of at least one other therapeutic treatment, and pharmaceutical compositions for combination therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10188691-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780881-B2 |
priorityDate |
2006-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |