http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101674809-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8925b769d645f9ff06af9f4b189f6a99 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate | 2008-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d785fb7f6b2483f1379872a52687203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a47f4b0a15ed43d4f69489d9cb99f8fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93b11dbca62084c740b6af85b8abbf9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00c9db961825371892b450b12be1e56d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d09873cbbaccc0a4a3db9083ed38d642 |
publicationDate | 2010-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101674809-A |
titleOfInvention | Be used to improve the autoprecipitation pharmaceutical preparation of release of active ingredients |
abstract | The present invention relates to the novel medicament preparation, be used for, perhaps even the time in several weeks, continue release of active ingredients (AP) at several days.First aspect present invention relates to a kind of liquid pharmaceutical formulation, it contains at least a active component (AP) and waterborne suspension, described waterborne suspension is based on the colloidal solid of polymer (PO), wherein said preparation satisfies following four conditions: (a) polymer (PO) is a polyamino acid, contain glutaminic acid residue, each all has wherein a part of glutaminic acid residue and hangs cation group (CG) from above, described cation group is identical separately or different, each all has another part glutaminic acid residue and hangs hydrophobic group (GH) from above, described hydrophobic group (GH) is identical separately or different, and (b) the pHf value of the pH of described preparation is 3.0-6.5; (c) under the pHf value, this polymer (PO) forms colloid solution, and it is spontaneous to be not covalently and active component (AP) combination; And (d) the described preparation of 1ml and the test buffer solution Tp mixing period of 1ml volume between precipitate.The invention still further relates to a kind of method of described preparation and method that a kind of preparation contains the medicine of described preparation of preparing. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109562064-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111698999-A |
priorityDate | 2007-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 675.