http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101654426-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e20991240ea81427169ce8115755fedc |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-20 |
filingDate | 2008-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fc276798a0b1299d615862955a38ac1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dcc5801247715b485a829e592fa7f4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_780c5a1e05146a6c7a6bb9a380fe0459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f583969a453fbb2470390cc8d56936f2 |
publicationDate | 2010-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101654426-A |
titleOfInvention | Method for preparing ilomastat |
abstract | The invention relates to a new method for preparing ilomastat, which comprises the following steps of: reacting a tryptophan methyl ester hydrochloride with a methylamine to prepare tryptophanyl methylamine; performing a condensation reaction between the tryptophanyl methylamine and a tert-butyl acetate succinate derivative to prepare a midbody of a formula (IV); removing the tert-butyl from the midbody of formula (IV) to form a midbody of a formula (V); and performing a condensation reaction between the midbody of formula (V) and a free hydroxylamine to form the ilomastat. The method of the invention is simple in the process and low in the cost. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105884674-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435514-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105884674-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103435514-A |
priorityDate | 2008-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.