http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101652366-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21092dbd0c8a37c0a396683bae2ca7ef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2008-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32ab14486a9d3d0026a85d2d165e469e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0dcd0d7d30d3c0305dd1cb3fa48faf4 |
| publicationDate | 2010-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101652366-A |
| titleOfInvention | New classical antifolates |
| abstract | Antifol compound and pharmaceutically acceptable ester class, amides, salt, solvate and the prodrug of (I) structure that the present invention relates to have formula, wherein X is CHR9 or NR9; Y1, Y2 and Y3 independently are O or S; V1 and V2 independently are O, S or NZ; Z is H, the optional alkyl that replaces, the optional alkenyl that replaces, optional alkynyl or the alkaryl that replaces; R1 and R2 independently are H, the optional alkyl that replaces, the optional alkenyl that replaces, optional alkynyl or the alkaryl that replaces; R3 is H, the optional alkyl that replaces, the optional alkenyl that replaces, the optional alkynyl that replaces, optional alkoxyl group, hydroxyl or the halogen that replaces; And R4, R5, R6, R7, R8 and R9 independently be H, the optional alkyl that replaces, the optional alkenyl that replaces, the optional alkynyl that replaces, acyl group ,-C (O)-alkyl ,-C (O)-alkenyl or-C (O)-alkynyl.Described compound is used for the treatment of various disease conditions, comprises abnormal cell proliferation, inflammatory diseases, asthma and arthritic pharmaceutical composition and method. |
| priorityDate | 2007-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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