| abstract |
The invention provides chemical compound and its pharmaceutical composition of being used to regulate the channel activating protease enzyme, and the method for using these compounds for treating, improvement or the prevention disease relevant with the channel activating protease enzyme, described channel activating protease enzyme comprises prostatein enzyme, PRSS22, TMPRSS11 (for example TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), protein lyase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A or neutrophil elastoser without limitation. |