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publicationDate 2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101627131-A
titleOfInvention Method for determining preeclampsia risk
abstract A method for determining the risk of a mother of a fetus to develop preeclampsia during pregnancy comprising: (a) providing a sample of genomic DNA from an individual related to the fetus; (b) analyzing the DNA for the presence of one or more mutations in the PP13 gene; and (c) determining the risk of the mother on the basis of the presence of the mutations. Also disclosed are mutated PP13 protein variants, and a kit for use in the method of the invention comprising DNA probes for specific genomic sequences of the PP13 native gene and/or mutated sequences thereof.
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