http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101619059-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_befa87f7a3a8515a06542874a0967ef2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 |
| filingDate | 2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45dc42e6cbe9dba8ec11eb84c368c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7afc64d040bb0b2011f3fd45a6a70d80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03918c5a29568aa501a8476629c101a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7182cd017ec9be71b43bf4f7a6f6b724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11371f7db185c569a80408915b3a783a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7acbf882480b0aac3add22d6181ce18f |
| publicationDate | 2011-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101619059-B |
| titleOfInvention | Method for preparing osemozotan hydrochloride |
| abstract | The invention discloses a method for preparing osemozotan hydrochloride and an intermediate thereof, namely (2R)-N-[3-(1, 3-benzodioxol-5-alkoxyl)propyl]-1, 4-benzodioxan-2-methanamide. In the method, 1,4-benzodioxan-2-carboxylic acid serving as an initial raw material is resolved through dehydroabietylamine, acylated or not acylated, and condensated with 3-(1,3-benzodioxol-5-alkoxyl) propylamine hydrochloride (V), and then the condensed product is subjected to reduction and salifying reaction to product the osemozotan hydrochloride with good optical purity through reduction and salt-forming reactions. The method has the advantages of cheap and easily-obtained raw material, short synthetic route, less reaction steps, mild reaction conditions, easy separation and purification of various intermediates, and suitable industrialized production. |
| priorityDate | 2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID143919965 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465453728 |
Total number of triples: 22.