Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f447d8315e8cf777897a7544d3fc2b43 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-385 |
filingDate |
2009-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52bb67d13f5b18170c9dc2e2448fb50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f365ab8ba8e31576d7450033ebf580cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_516506efe9c28255f11c4a9a0ff60807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db6537a257698951166375871fdc86b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db68733a6c51c051f996fca66038eb11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f319e5da88d4a9f5a1dffa3bd391d9b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab026858a7b341b5de5d630190454a21 |
publicationDate |
2011-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101618222-B |
titleOfInvention |
Anethol trithione and phospholipid compound and preparation method thereof |
abstract |
The invention relates to a peroral anethol trithione preparation and a preparation method thereof, belonging to the field of pharmaceutical preparations, The preparation method comprises the following steps: dissolving anethol trithione and phospholipid in a compound mode to one or a plurality of fatty acid triglycerides to prepare soft capsules and/or palletizing the phospholipid compound and suitable pharmaceutical excipient to further prepare enteric-coated capsules. Compared with preparations sold in markets, animal experiment results show that the prepared new preparation of the phospholipid compound obviously improves the peroral bioavailability of the anethol trithione and the pharmaceutical concentration in the target tissue liver and predicts favorable liver protection efficacy and cholagogic efficacy. |
priorityDate |
2008-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |