http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101600721-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4365 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
filingDate | 2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e4b3109f06c0adcdb85f9afdf830be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86713eb1e15a03f2674066d6e1d97c5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e720719e7454efb6cff9e7bc4fc4913 |
publicationDate | 2009-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101600721-A |
titleOfInvention | (S)-(+)-and methyl-α-(2-chloro-phenyl-)-6, the preparation method of the polymorphic form form I of 7-dihydro-thieno-[3,2-c] pyridines-5 (4H)-acetic ester hydrosulfate |
abstract | The present invention relates to by in the presence of solvent, making (S)-(+)-methyl-α-(2-chloro-phenyl-)-6,7-dihydro-thieno-[3,2-c] pyridine-5 (4H)-acetic ester and sulfuric acid reaction come (S)-(+)-methyl-α-(2-chloro-phenyl-)-6 of preparation formula I, 7-dihydro-thieno-[3,2-c] method of pharmaceutically acceptable polymorphic form form I of pyridine-5 (4H)-acetic ester hydrosulfate, this method comprises, with (S)-(+)-methyl-α-(2-chloro-phenyl-)-6,7-dihydro-thieno-[3,2-c] pyridines-5 (4H)-acetic ester is dissolved in ether; Make this solution and Cn 6 -Cn 11 Pure and mild vitriolic solution mixes; With the formula I compound that obtains like this from the mother liquor recovery. |
priorityDate | 2006-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.