http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101600721-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
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filingDate 2007-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e4b3109f06c0adcdb85f9afdf830be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86713eb1e15a03f2674066d6e1d97c5a
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publicationDate 2009-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101600721-A
titleOfInvention (S)-(+)-and methyl-α-(2-chloro-phenyl-)-6, the preparation method of the polymorphic form form I of 7-dihydro-thieno-[3,2-c] pyridines-5 (4H)-acetic ester hydrosulfate
abstract The present invention relates to by in the presence of solvent, making (S)-(+)-methyl-α-(2-chloro-phenyl-)-6,7-dihydro-thieno-[3,2-c] pyridine-5 (4H)-acetic ester and sulfuric acid reaction come (S)-(+)-methyl-α-(2-chloro-phenyl-)-6 of preparation formula I, 7-dihydro-thieno-[3,2-c] method of pharmaceutically acceptable polymorphic form form I of pyridine-5 (4H)-acetic ester hydrosulfate, this method comprises, with (S)-(+)-methyl-α-(2-chloro-phenyl-)-6,7-dihydro-thieno-[3,2-c] pyridines-5 (4H)-acetic ester is dissolved in ether; Make this solution and Cn 6 -Cn 11 Pure and mild vitriolic solution mixes; With the formula I compound that obtains like this from the mother liquor recovery.
priorityDate 2006-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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