| abstract |
The invention provides chemical compound and its pharmaceutical composition of being used to regulate the channel activating protease enzyme, and the method for using described compounds for treating, alleviation or the prevention disease relevant with the channel activating protease enzyme, described protease includes but not limited to prostatein enzyme, PRSS22, TMPRSS11 (for example TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), protein lyase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A or neutrophil's elastoser. |