| abstract |
The present invention relates to have the LHRH receptor antagonist activity, has the decapeptide derivative that suppresses the effect of hypophysis secretion gonad-stimulating hormone, the effect of inhibition glandular secretion steroid hormone, its preparation method contains their pharmaceutical composition and their purposes in treatment prostate cancer, carcinoma of endometrium, the sexual hormoue dependence relative disease relevant with reproduction, contraception etc. |