| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed4ace5a2305a45c8d9dd46de7d464d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7daa5abc6a15c256aa178ec92c5ce47e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70535 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2007-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_673895b62331fa6feb7ad44db0a0b75e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4c61ec98f66d2dd069496d88277e10f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68324853662ed21f4584f2539c6b4cd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fa26e7aee46879bd79d3a8d146e32e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9bd2e2d03528bcdf02c4e82cef6fd84 |
| publicationDate |
2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-101595128-B |
| titleOfInvention |
Transgenic animal with enhanced immune response and method for the preparation thereof |
| abstract |
The present invention provides a method for producing a transgenic (Tg) non-human animal capable of developing an enhanced humoral immune response against an antigen as compared to a non-transgenic control animal of the same species, comprising introducing into said non-human animal a genetic construct providing for enhanced MHC class I-related neonatal Fc receptor (FcRn) activity. Also provided a Tg non-human animal comprising a genetic construct providing for enhanced FcRn activity, as well as the use of such animal in a non- therapeutical method. Therapeutic genetic constructs and methods are also provided. The present invention further provides methods for producing immunoglobulins. |
| priorityDate |
2006-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |