http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101591645-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e2b7361978d9ff4829de745aac79548 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42c6b17fd6c3d77379a441130020cac6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80472c03afcda60bdfe68072d464adb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b834f41699bb861cc20897ad7a324c52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a8f01a0920fe9cf157df1803e02af90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_261aa1bea5619aea64ddc397046a6b5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd8efe9207d60b24cbac7bffa8e7381 |
| publicationDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101591645-B |
| titleOfInvention | Screening method of anti-HIV drug |
| abstract | The invention discloses a screening method of an anti-HIV drug, which comprises the following steps: a sample to be tested is added to a fusion protein which expresses hA3G and reporter gene and a Vif cell; the blocking effect of the sample on Vif pathway is judged by investigating the quantity of the encoding products of the reporter gene; whether the initially chosen sample is an inhibitor in the pathway of proteasome degradation is further judged to screen out the anti-HIV drug. In the method provided by the invention, a hA3G is taken as a target point, solves the problem of drug resistance caused by high mutation of viruses and has no cross resistance with the anti-HIV-1 drug used in clinical application for the moment. |
| priorityDate | 2008-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.