http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101583613-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2008-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e210d9bd9dc4ae059e8594fce726678 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_153132bd94c08bef83d3e883f159750c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11d5eea56af96a8e24807219e6f241be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e880bf99d68dfb33a11c1ec4aa1fc328 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d82f83986619d9ec7748f9d5682f5db1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_088fb14c2419ecefeadc9da89cd70f8d |
| publicationDate | 2009-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101583613-A |
| titleOfInvention | Method for production of aryl-substituted annelated pyrimidines |
| abstract | The invention relates to a method for production of aryl-substituted annelated pyrimidines of general formula (I), where L<1> to L<5>=H, halogen, CN, NO2, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, etc., Y<1> to Y<3> = C-R<Y> or N, R<Y> = H or optionally substituted C1-C4 alkyl or two adjacent R<Y> groups together form a ring, X = OH, Cl or Br, comprising: i) the reaction of a 2-phenylmalonate with a compound (III) or a tautomer thereof, in the presence of a suitable base, with continuous removal of the alcohol of formula R-OH, formed during the reaction, under reduced pressure, to give a compound of formula (I) or a salt thereof, where X = OH and in the case that X in compounds of general formula (I) = chlorine or bromine, ii) the reaction of the compounds of formula (I) obtained in step (i) or the salt thereof with a halogenating agent. |
| priorityDate | 2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.