Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b55c349b43c3ecba4977fd52cc8f8c67 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2013-00646 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2007-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d725ede90509269ae003a594e3b827b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba84ad48c9f1b4dd659179322fd3ab65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed87d4efd7bbedbb6be5e1a2312d91c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e793aa64bca58099bb70bbf4121cb0b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cdc8c65a303d25d60ee0a55323f7cb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adf394ac8bd3f57f1dac9e7c4caacf36 |
publicationDate |
2009-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101573115-A |
titleOfInvention |
Method for prevention of coloration in donepezil-containing skin adhesive preparation, and method for reducing the production of donepezil analogue in donepezil-containing skin adhesive preparation |
abstract |
To prevent the coloration in a donepezil-containing skin adhesive preparation to achieve the appearance having a natural color, or the like. Disclosed is a method for preventing the coloration in a skin adhesive preparation comprising a substrate and an adhesive layer, wherein the adhesive layer comprises an adhesive agent and donepezil. The method is characterized by adding ascorbic acid or a metal salt or ester thereof and a metabisulfite metal salt to the adhesive layer. Preferably, the method comprises the steps of: providing a preparation product comprising the adhesive agent, donepezil, ascorbic acid or a metal salt or ester thereof and a metabisulfite metal salt; and applying the preparation product onto the surface of the substrate to form the adhesive layer. |
priorityDate |
2006-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |