| abstract |
The present invention relates to dual modulators of the serotonin 5-HT2a and dopamine D3 receptors which are represented by the general formula (I) wherein R<1>, R<2> and A are as defined in the specification, to a process for the manufacture thereof, as well as to pharmaceutically acceptable salts thereof for the manufacture of a medicament for the treatment or prevention of cognitive disorders, drug addiction, depression, anxiety, drug dependence, dementias, memory impairment, psychotic disorders comprising schizophrenia, schizoaffective disorders, bipolar disease, mania, psychotic depression, and psychoses comprising paranoia and delusions. |