| titleOfInvention |
1,2,3,5,11,11a- hexahydro-3,3-dimethyl-1-oxo-6H-glyoxaline [3', 4': 1,2] pyridine [3,4-b] diindyl-2-substituted methyl acetate, as well as preparation and application thereof |
| abstract |
The invention discloses compounds shown in a general formula (I) with vasodilation activity, or pharmaceutically acceptable salts thereof, wherein R is -CH(CH3)CH2CH3, -CH(CH3)2, -CH2CH(CH3)2, -CH3, H, -CH2C6H5, -CH2C6H4-OH-p, indole-5-ylmethylene, imidazole-4-ylmethylene, -CH2CH2SCH3, -CH2CO2CH3, -CH2CH2CO2CH3, -CH2OH, -CH(OH)CH3, -CH2CH2CH2NHC(NH)NH2, -CH2CONH2 or -CH2CH2CONH2. |