http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101491678-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40a2db9d7be353c7b90d4be6ee88e904 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 |
| filingDate | 2009-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e04c3706531019f30b47f8e80238ebed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7882af436baa7d9a68e0986ab2cbb0f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c61533749748bdb9a761f116e956c842 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640e57e50cd1728f8c91eae5432a4295 |
| publicationDate | 2009-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101491678-A |
| titleOfInvention | Preparation method of injector using tween-80 as solubilizer |
| abstract | The invention provides a method for preparing an injection. The method comprises the following steps: mixing a purified human body accepted liquid medicine for injection with refined Tween-80, and adding water for injection into the mixture until final concentration of the Tween-80 is between 1 and 5 gram/liter so as to obtain the injection. The method for refining the Tween-80 comprises the following steps: taking the Tween-80 to be added with the water for injection to prepare a solution with mass concentration of between 10 and 30 percent; and keeping slight boiling for 5 to 10 minutes after the solution is boiled, cooling the solution to be between 70 and 80 DEG C, adding 1 to 5 gram/liter activated carbon into the solution, stirring the solution to be cooled at a temperature of between 50 and 60 DEG C, and filtering the solution to obtain a refined Tween-80 aqueous solution. The method has the advantages that, according to the refining method, compared with the Tween-80 not refined, the refined Tween-80 has obviously reduced toxicity, and greatly improved safety coefficient of the Tween-80. Injection, in particular intravenous injection, prepared by the refined Tween-80 can reduce rate of adverse reaction after clinical application, and improve the safety of clinical medication. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104399083-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102379956-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110639464-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106309904-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020062928-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106806358-A |
| priorityDate | 2009-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.