| abstract |
The present invention relates to a benzylphenyl glucopyranoside derivative having an excellent inhibitory effect on human SGLT1 and/or SGLT2 activity. There is provided a compound or a pharmacologically acceptable salt thereof represented by the following general formula (I): wherein R 1 represents a hydrogen atom, an amino group, a hydroxy C 1 -C 6 alkyl group, etc.; R 2 represents a hydrogen atom, etc.; R 3 represents a C 1 -C 6 alkyl group, a hydroxy C 1 -C 6 alkyl group, etc.; R 4 represents a hydrogen atom, a C 2 -C 7 acyl group, etc.; R 5 , R 6 , R 7 , and R 8 are the same or different and each represents a hydrogen atom or a C 1 -C 6 alkyl group, provided that R 5 , R 6 , R 7 and R 8 are not hydrogen atoms at the same time; n is 0 to 4; and X is CH or N. |