http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101463014-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
filingDate | 2008-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf6f8f0e715e15e02a99b5173035a53e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cda3c4dc22cfb309e3e475ee9871098e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b03afd962420a9e596080ab6a0ad00ff |
publicationDate | 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101463014-B |
titleOfInvention | Diaryl benzo pyridine derivative, and its pharmaceutical composition and use thereof |
abstract | The invention belongs to the medicine technical field, and provides a series of diaryl benzo pyrimidine derivatives (DABPs) of formula I, pharmaceutical salt thereof, stereochemical isomers thereof, a hydrate and a solvolyte thereof, a polycrystal and an eutectic crystal thereof, a precursor and a derivative thereof with the same biological function, a preparation method thereof and application of a composition containing one or a plurality of the compounds to related medicines for treating AIDS and the like. The results of pharmacological experiments prove that the compounds have obvious anti-HIV-1 virus activity, can effectively inhibit replication of MT-4 cells infected by the HIV-1 virus, and have low cytotoxicity. |
priorityDate | 2008-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.