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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
filingDate 2008-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf6f8f0e715e15e02a99b5173035a53e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cda3c4dc22cfb309e3e475ee9871098e
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publicationDate 2013-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101463014-B
titleOfInvention Diaryl benzo pyridine derivative, and its pharmaceutical composition and use thereof
abstract The invention belongs to the medicine technical field, and provides a series of diaryl benzo pyrimidine derivatives (DABPs) of formula I, pharmaceutical salt thereof, stereochemical isomers thereof, a hydrate and a solvolyte thereof, a polycrystal and an eutectic crystal thereof, a precursor and a derivative thereof with the same biological function, a preparation method thereof and application of a composition containing one or a plurality of the compounds to related medicines for treating AIDS and the like. The results of pharmacological experiments prove that the compounds have obvious anti-HIV-1 virus activity, can effectively inhibit replication of MT-4 cells infected by the HIV-1 virus, and have low cytotoxicity.
priorityDate 2008-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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