http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101456872-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2009-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c465525b6ef3e067ed7af6cf053966a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a99492fdca39bd75626e83e255de9c6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ea57f6d12c4410e5eb834bef460b266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d931f9ebcfa81017f3c85bb1630253b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ff6645d7cba5834394bd91f67e9c453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_829cb9f2446d5ca0b2bb11f27acf672d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c8c8a627176d82b148f777186ae567a |
| publicationDate | 2009-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101456872-A |
| titleOfInvention | Thiazole[3,2-a] miazine derivates and use thereof |
| abstract | The invention belongs to the technical field of medicine, and relates to thiazole-[3, 2-a]-pyrimidine derivatives and application thereof. A structural general formula is as right: the thiazole-[3, 2-a]-pyrimidine derivatives and salts added by pharmaceutically applicable acid of the compounds are used as acetylcholine esterase inhibitors, wherein R1 can be optionally substituted by one or two alkyls independently selected from C1 to C6, alkoxyl of C1 to C6, aminoalkoxyl optionally substituted by C1 to C10, substituted or non-substituted amino formoxyl alkoxyl, hydroxyl and substituted group of halogen; R2 is independently selected from hydrogen, alkyl of C1 to C6, phenyl substituted by aminoalkoxyl optionally substituted by C1 to C10, phenyl substituted by substituted or non-substituted amino formoxyl alkoxyl, and phenyl substituted by hydroxyl; and R3 is independently selected from methyl or oxethyl. The derivatives are used for enhancing memory of patients suffering from dementia and Alzheimer's diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104530090-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012439-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104530090-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012439-B |
| priorityDate | 2008-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.