http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101450920-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_804f1526dd1189df3a57e0f4639cb242 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-26 |
| filingDate | 2007-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e2c443f10c81e94bb9fb40d811889e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b72ed30ab810ec6ca223db47a284f9 |
| publicationDate | 2009-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101450920-A |
| titleOfInvention | Method for producing metformin hydrochloride large particle crystal |
| abstract | The invention provides a method for producing large-grained crystals of metformin hydrochloride in the technical field of chemical synthesis. The invention adopts a technical proposal that: a crude product of metformin hydrochloride obtained through synthesis of dimethylammonium chloride and dicyandiamide is firstly washed with absolute ethanol; after a parent liquid washed by ethanol is separated, the obtained crude product of metformin hydrochloride is put into a purified water of which the weight is three times of the weight of the crude product of metformin hydrochloride, heated to 65 to 75 DEG C for circumfluence, stirred to be cooled to 40 to 50 DEG C, and stood to be cooled to 20 DEG C, then the parent liquid is separated, and thus large-grained crystals of metformin hydrochloride is obtained. The granularity of 95 percent of the large-grained crystals of metformin hydrochloride exceeds 40 meshes, the large-grained crystals of metformin hydrochloride has a taste of edible monosodium glutamate, can meet the requirements of customers, and contributes to the reduction of production cost. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248409-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113248409-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102153489-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113292460-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107337618-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106795104-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016059507-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112679389-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106008277-A |
| priorityDate | 2007-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.