http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101429159-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3c1686c02a62643727ab319c4570e34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-233 |
filingDate | 2007-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_694be1e13cb9559ce71a81a5041746e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e703ee100fd961d728573936abd99cd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3a017220ebc14c476bdc3b73595a60b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eead0e508b3b490ee5d7ec573deb704d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35db64aae970fe9da70848252effe0cf |
publicationDate | 2012-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101429159-B |
titleOfInvention | Synthesis of 1-R-2,3-dihydrogen-1H-quinoline-4-ketone |
abstract | The invention relates to a method for synthesizing 1-R-2, 3-dihydrogen-1H-quinoline-4-ketone, which mainly solves the technical problems that the prior synthesis method is difficult to amplify raw material, long in route, inconvenient in reaction operation, and the like. The method for synthesizing 1-R-2, 3-dihydrogen-1H-quinoline-4-ketone is characterized by comprising the following steps: a. 4-hydroxyquinoline is taken as a raw material and reacts with alkyl halogenated matter, benzyl halogenated matter or alkyl sulphonic acid ester in solvent to form ketene; b. the ketene dissolves in the solvent, and a reducing agent is added to the solvent so as to obtain corresponding alcohol; and c. oxidant is added to the corresponding alcohol dissolved in the solvent, so as to obtain the 1-R-2, 3-dihydrogen-1H-quinoline-4-ketone through oxidation. |
priorityDate | 2007-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.