http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101417997-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7826e82a59639f553bfb024dfb2a0ea5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 |
filingDate | 2008-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6e083dd83aab8ec9db0350b2c573db8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d8704ac940d9250b411cd3132deb2cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eac8afb64125177eb8de945d4e4c826 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f7c574ff7eb6e6a390bb149e3573ec5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c805bdf759f4a967bb6547e9db313470 |
publicationDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101417997-B |
titleOfInvention | Inhibitor compounds containing benzo2-aminoimidazloe skeleton and preparation method thereof |
abstract | The invention belongs to the field of chemical synthesis, and relates to an inhibitor compound containing benzo 2-amino-imidazole skeleton, a method for preparing the same and application thereof. The inhibitor compound contains a new core skeleton of 1, 2, 5-trisubstituted-benzo-2-amino-imidazole. The invention optimizes the effect on activity through different substituents by comparing the time under the guidance of in vivo activity selection and preferably selects a compound which generates obvious inhibition on thrombin. The synthesis method has simple steps, operations and separations, the reagents used in the method are commonly used reagents, the route is shorter, and each step has higher yield. The obtained target compound has effect on inhibiting the generation of the thrombin through an activity test. |
priorityDate | 2008-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.