http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101416945-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b96051732f16de8bbc483260d8496af |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate | 2007-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a83bc44a785afdce27eb7f60ddf1d23 |
publicationDate | 2009-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101416945-A |
titleOfInvention | Preparation method of azithromycin fine granule |
abstract | The invention pertains to a preparation method adopting a spray-drying method to encapsulate drugs into miniature capsule fine granules, more particularly relates to the preparation of azithromycin fine granules. The preparation method comprises the steps that: (1) poly-acrylic acid resin is soaked in an organic solvent, stirred, dissolved and prepared into a poly-acrylic acid resin solution after being filtered by a mesh sieve; (2) azithromycin material is added into the poly-acrylic acid resin solution obtained from Step 1), thus obtaining a mixed material; (3) the mixed material of Step (2) is treated with spray-drying, and miniature capsules are collected; and (4) the miniature capsules obtained from the Step (3) are added with a sweet food additive, mixed evenly, dried and prepared into granules. The preparation method prepares the azithromycin material solution into the miniature capsules by the way of spray-drying and solves the disagreeable taste effect caused by the bitterness of azithromycin preparations by sweet layers wrapping the outer layers of the miniature capsules. The solving of the taste of the azithromycin preparations cause the granules to be convenient for users to take, especially for children and patients with chronic diseases and needing to take the granules for a long term. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110123788-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110755404-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111973560-A |
priorityDate | 2007-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.