| abstract |
The invention provides a pyrimidine substituted phenylpropionic acid compound shown in formula (I), and application of enantiomer, racemic modification, a pharmaceutically acceptable salt of the compound, or a mixture of the enantiomer, the racemic modification and the pharmaceutically acceptable salt of the compound to preparation of medicine for preventing and/or treating diabetes mellitus. The compound as PPAR-gamma excitant can participate in the regulation of genetic transcription through activating PXR/PPAR heterodimer, thereby effectively treating and/or preventing the diabetes mellitus. The invention also provides a medicine composition which contains the compound and has the effect of preventing and/or treating the diabetes mellitus. |