http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101407522-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e20991240ea81427169ce8115755fedc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
filingDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_974020b124764f671c75bd022758b32e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae28fb0a44bb97ea1492850db96f6ad0 |
publicationDate | 2009-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101407522-A |
titleOfInvention | Preparation of amyrolin and derivatives thereof |
abstract | The invention relates to a synthesizing method and preparing process for seselin and the derivatives. The method takes substituted hydroxyphenol as a raw material, and after Pechmann reaction, acetylation, Fries rearrangement, cyclization, reduction and dehydration, the seselin compound can be obtained. The method has the advantages of simple operation of each step, controllable conditions, easily obtained reagent, convenient purification, single product and high yield. The synthesizing route overcomes the defects of low yield and being difficult to remove isomers of the existing methods. The seselin and the derivatives which are taken as the important bioactive substance and medical intermediate have good application prospect in anti-inflammatory, anti-fungus and anti-tumor aspects, particularly playing a key role in synthesizing candidate anti-HIV agents. The synthesizing route and the method have high application value and wide application prospect. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109303776-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112062773-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107094782-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109303776-A |
priorityDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.