Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d94573ab2c57e8b193f3a22accddf9fe |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_941ddb849daaa111443570678487ac00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0197f98e601cabd10475e3640955980a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f93af22600fa6a996617abd2abd4a84f |
publicationDate |
2009-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101390826-A |
titleOfInvention |
Magnetic tumour target polymer nano vesicle and preparation method thereof |
abstract |
The invention discloses a magnetic tumor targeting polymer nano-capsule which contains the following ingredients by weight portion: 5-20 portions of amphiphilic copolymer of folic acid terminated polyethylene glycol and polylactic acid, one portion of paramagnetic nano-particles, a portion of hydrophilic anticancer medicine. The invention also discloses the preparation method of the nano-capsule; the preparation method adopts amphiphilic copolymer of folic acid terminated polyethylene glycol and polylactic acid as the raw material; ferroferric oxide nano-particles and hydrophilic anticancer medicine are encapsulated to obtain the nano-capsule through the ultrasonic emulsifying method. The nano-capsule can further improve the release efficiency and local concentration of the medicine, reduce the medicine dosage, the toxic and side effects. The magnetic tumor targeting polymer nano-capsule has excellent magnetic resonance imaging characteristic and has great research values and application prospects in the treatment and early diagnosis fields of cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105175758-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104721140-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112190563-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104721140-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101773676-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111973762-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102145177-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102145177-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103976953-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113694027-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113694027-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110638753-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105175758-B |
priorityDate |
2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |