http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101386595-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d8879615a983dd87fb7eb03b5bd6a72 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-22 |
| filingDate | 2008-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eca2911f6c8ab1a09ff0580d8dd1495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd5048b0044f4096087c85d59c012a85 |
| publicationDate | 2012-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101386595-B |
| titleOfInvention | Chemical synthesis method of 10-methoxyl-5H-dibenz[b,f]azapine |
| abstract | The invention provides a method for chemically synthesizing 10-methoxy-5H-dibenzo[b, f]azepin. The method comprises the following steps: using 10, 11-dibromo-imino-dibenzyl as a raw material to react with potassium hydroxide or potassium methoxide in methanol so to generate the10-methoxy-5H-dibenzo[b, f]azepin; preferably, firstly, adding the potassium hydroxide or the potassium methoxide in the methanol, adding the 10, 11-dibromo-imino-dibenzyl into the mixture after heating up and refluxing the mixture, and reducing the pressure and distilling the methanol after heating up and refluxing the mixture as well as keeping the temperature for a period of time; secondly, adding water into the mixture, and stirring, filtering and drying the mixture to obtain a crude product of the 10-methoxy-5H-dibenzo[b, f]azepin; and finally, adding solvent into the crude product for refinement to obtain the refined product of the 10-methoxy-5H-dibenzo[b, f]azepin. The method has the advantages of reasonable process and high reaction yield, and suitability for large-scale industrial production. |
| priorityDate | 2008-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415053968 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID78424 |
Total number of triples: 14.