http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101357905-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc12f48618be8909d7af78e046b536b7 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 |
filingDate | 2007-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34097f934799f889a0a55a610783d65b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c97dce7a0bb0659b905bfb069925f89d |
publicationDate | 2012-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101357905-B |
titleOfInvention | Method for preparing 4-[3-chloro-4-(3-fluoro-benzyloxy)-anilino]-6-substituted amido-quinazoline derivative |
abstract | The invention relates to a preparation method of 4-(3-chlorine-4-(3-fluoride-benzyloxy)-anilino)-6-substituded amino-quinazoline derivatives (chemical formula I), comprising nucleophilic substitution reaction of 3-chlorine-4-(3-fluoride-benzyloxy)-aniline (compound II) and the compound indicated in the general formula III in a proton polar organic solvent. The method is low in production cost, and is suitable for industrial production. |
priorityDate | 2007-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.