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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-12
filingDate 2006-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fa6eb008740ab3174d4fbe42f31d4fc
publicationDate 2009-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-101356177-A
titleOfInvention The use of oripavine as a starting material for buprenorphine
abstract There is provided a method for the synthesis of norbuprenorphine, and ultimately buprenorphine, utilizing oripavine as the starting material. Conventional methods of producing buprenorphine utilize thebaine as the starting material, requiring an O-demethylation step, typically a low to moderate yield transformation. The present use of oripavine as a starting material does not require an O-demethylation step, since the oripavine molecule lacks an O-3 methyl group.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102382118-A
priorityDate 2006-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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