| abstract |
To provide a process for production of <18>F-TAFDG, which can produce of <18>F-TAFDG with a high radioactive fluorination yield. [MEANS FOR SOLVING PROBLEMS] A process for production of a compound labeled with radioactive fluorine, comprising the steps of: preparing a reaction solution comprising a [<18>F]fluoride ion, a phase transfer catalyst, 1, 3, 4, 6-tetra -O-acetyl-2-O-trifluoromethanesulfonyl-ss-D-mannopyranose (which is a labeled precursor compound) and a solvent; and subjecting the reaction solution to a reaction under specified reaction conditions to yield 1, 3, 4, 6-tetra -O-acetyl-2-[<18>F]fluoro-2-deoxyglucose, wherein the solvent contains water. |