Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 |
filingDate |
2008-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3468aef26b30d15facfb5e73352f3b60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f661cf1bf691cf24c9665184c08f4dfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da68f070d3927b111b976da91f75a19c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8db4e6323de860ef9cb80734378e5e97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c0ca2b5a277281d2ea3038e565f904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d31c836b1a78ab6eae007cee2ab5ffd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_378e65ad5a85d9b89de520d150e38834 |
publicationDate |
2012-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101328123-B |
titleOfInvention |
5-oxo-substituted benzene acryloyl quinate methyl ester compound and use thereof |
abstract |
The invention provides a 5-oxygen-substituted benzene ethylenic propionyl quinic acid methyl compound and an officinal salt (I) thereof as well as an important intermediate of 5-oxygen-[3-substituted benzene ethylenic propionyl]-3, 4-acetone fork quinic acid methyl ester compound for preparing the compound (I) and an officinal salt (II) thereof. The compound (I) and the compound (II) have the functions of restraining DNA of hepatitis b virus from copying and reducing the expression of a surface antigen of the hepatitis b virus and can be applied to prepare a medicine for treating hepatitis b virus infectious diseases. The structural formulas of the compound (I) and the compound (II) are shown above. |
priorityDate |
2008-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |