Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba86765794faec560ac8e444ab027f9b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2006-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2008-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-101309699-A |
titleOfInvention |
Stabilized virus-like particles and epitope display systems |
abstract |
A chimeric polypeptide is disclosed that comprises: i) a first portion that self-assembles into an organized, repetitive, supramolecular structure that contains at least about 9 subunits, covalently linked to ii) a second polypeptide portion that comprises a peptide having a length of about 15 to about 80 amino acid residues. The second portion peptide self-assembles to form parallel multimers. A contemplated chimeric polypeptide forms a particle that is more stable than is a particle formed from a first polypeptide that is otherwise identical in sequence, but lacks the covalently linked self-binding peptide sequence of the second polypeptide portion. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103118709-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107080833-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107488218-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107488218-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107522777-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107522777-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107488217-A |
priorityDate |
2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |