http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101307048-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a12de89b1d36825acdae44a29aff4665 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D411-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D411-04 |
| filingDate | 2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8baebedb95d1392cebd6b2d8846aa61d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9568c6e8e144e9b47f8ed98794252c |
| publicationDate | 2011-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101307048-B |
| titleOfInvention | Stereoselective method for preparing lamivudine |
| abstract | The invention discloses a stereoselective preparation method of lamivudine, which comprises (a) carrying out a glycosylation reaction between a compound of formula (I) and cytosine or protected cytosine, and crystallizing and separating the reaction product to obtain The intermediate formula (II); (b) deprotecting the intermediate formula (II) to obtain lamivudine. The method of the invention has mild reaction conditions, high stereoselectivity of intermediates, can separate diastereomers only by a simple crystallization method, is easy to operate, and is suitable for industrial production. |
| priorityDate | 2007-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.