abstract |
The present invention relates to a method for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist. The method comprises: administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7> and R<8> are as defined herein. |