http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101292034-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f98e77d1aba3a9c2fb565cc42cc7c76f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-77 |
filingDate | 2006-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63fb7815baf20e3d3aa9f874d9f97093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6432ed1586d6c55ceb6a7262960651b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9be97ad8f93895262b53e2226c9a061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf638374946b37e34605a050ce4924f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7ba391fcc98fab349ee25a61a1923b |
publicationDate | 2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101292034-A |
titleOfInvention | Rna antagonist compounds for the inhibition of apo-b100 expression |
abstract | Oligonucleotides directed against the Apo-B100 gene are provided for modulating the expression of Apo-B100. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding the Apo-Bl00. Methods of using these compounds for modulation of Apo-Bl00 expression and for the treatment of diseases associated with either overexpression of Apo-Bl00, expression of mutated Apo-Bl00 or both are provided. Examples of diseases are cancer such as lung, breast, colon, prostate, pancreas, lung, liver, thyroid, kidney, brain, testes, stomach, intestine, bowel, spinal cord, sinuses, bladder, urinary tract or ovaries cancers. The oligonucleotides may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid or a combination thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105008533-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023138689-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109477110-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109477110-B |
priorityDate | 2005-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 428.