http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101268066-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_207c148d0cfc11d05383db5abcce58d3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 |
| filingDate | 2006-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d0ffdef85211fe73a777380da27888a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a37a6aec2b4cb2f89149de8d0b049c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3819c9c414f8477303dec6f5e547806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72d0ad31a3252a3e3144f63cbfdfada9 |
| publicationDate | 2012-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101268066-B |
| titleOfInvention | A process for the preparation of sartan derivatives and intermediates useful in such process |
| abstract | The invention provides a process for the preparation of a sartan derivative of formula (I) (formula as filed in paper form) (I) wherein the substituents have the meaning indicated in the description, or a pharmaceutically acceptable salt thereof, comprising reacting 2-cyanophenylboronic acid or a derivative thereof with a p-halobenzyl-1H-imidazole derivative of formula (VI), (formula as filed in paper form) (VI) wherein (part of formula as filed in paper form), X, Y, R1 and R2 are as defined above, and Z is I, Br or Cl, in the presence of a transition metal catalyst and an inorganic or organic base. The invention also provides new intermediates of formula (V), (formula as filed in paper form) (V) wherein M is an alkali metal or an NR4R5R6R7 group; and of formula (II) (formula as filed in paper form) (II). |
| priorityDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.