| abstract |
The invention provides a chemical synthesis method of 4-chloromethyl-5-methyl-1, 3-dioxa cyclopentene-2-ketone, which comprises using 4, 5-dimethyl-1, 3-dioxa cyclopentene-2-ketone as raw material and uses sulfuryl chloride as chlorinating agent to process reflux reaction in organic solvent for 1-3h, evaporating out the solvent, rearranging for 1-4h at 70-100DEG C, and separating the reaction liquor after the rearrangement to obtain the 4-chloromethyl-5-methyl-1, 3-dioxa cyclopentene-2-ketone. The chemical synthesis method has the advantages of reasonable process conditions, reliable and safe production, high reaction total yield, low production cost, little discharge of three wastes and significant pratical, social and economic benefits. |