abstract |
This invention relates to a novel class of compounds, represented by the formula below, wherein the meanings of R<1> , R<2> and R<3> are indicated therein, which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsms K, L, S and B These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis, osteoarthritis and rheumatoid arthritis. |