http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101213198-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c539db959cc0106cab1662303f94fce |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 |
| filingDate | 2006-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6812721391c4bffce90258719256019f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf7aa835818d7e9633be1604efaadc34 |
| publicationDate | 2008-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-101213198-A |
| titleOfInvention | 1-[2',3'-dideoxy-3'C-(hydroxymethyl)-beta-D-erythro-pentofuranosyl] cytosine derivatives as HIV inhibitors |
| abstract | The invention relates to a compound of formula (I) and a salt acceptable by pharmacy, with the utility of curing or preventing HIV, in particular reverse transcriptase mutants which allow an obligate chain terminating nucleoside-or nucleotide phosphate to be excised from the nascent DNA strand by ATP-or pyrophosphate-mediated excision. Wherein, R<1> is independently H1-OR<3>, NHR<4> and C1-C4 alkyl; or, when n is 2, the adjacent R<1> together forms alkyl and R<2> is H; or when gem R<1> is C1-C4 alkyl, R<2> can also be C1-C4 alkyl; or when gem R<1>is -OR<3>, R<2> can also be -C(=O)OH or the acceptable ester in pharmacy; R<3> is dependently H or the acceptable ester in pharmacy; R<4> is dependently H or the acceptable acid amide acceptable in pharmacy; R<5> and R<6> are H or the medicine part before amine; n is 1, 2 and 3. |
| priorityDate | 2005-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 294.